New Test Identifies Heart Transplant Rejection - Without A Biopsy
Researchers have created a noninvasive way to detect heart-transplant rejection weeks or months earlier than previously possible. The test relies on the detection of increasing amounts of the donor's DNA in the blood of the recipient and does not require the removal of any heart tissue.
The test, called a cell-free DNA test, is different from another blood test, AlloMap, used to detect rejection. The commercially available AlloMap uses a blood sample to analyze the expression of immune-system genes involved in rejection. The researchers found that the cell-free DNA test outperformed AlloMap…