Susceptibility to Crohn's disease
Crohn’s disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated 0.15% of people in the developed world. Common symptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications. Researchers from the University of Liège, Belgium, have now uncovered an important clue to the susceptibility of individuals to this disease.
In a genome-wide association study with more than 300,000 single nucleotide polymorphisms (SNPs) – DNA sequence variations occurring when a single nucleotide in the genome…