Microbiology
Dr.Varaprasad Bobbarala M.Sc., Ph.D.
Chief Scientist,
Translational Research Institute of Molecular Sciences (TRIMS)
http://www.trimslabs.com/
E Mail : varaprasad@trimslabs.com,
E-mail: varaprasad.bobbarala@gmail.com
Skype: varaprasadbobbarala
Mobile : 9949129539
PROFILE
Expertise in the area of new drug discovery and development, in vitro&in vivo
efficacy studies, Cell based assays, Antioxidant studies and Analytical
chemistry. Management of projects and Involved actively in Drug…
The first observatory experiment to study the dynamic microbial life inside Earth's crust has just been completed. During the four-year subsurface experiment, the research team deployed the first in situ experimental microbial observatory systems below the flank of the Juan de Fuca Ridge, which is located off the coast of Washington (U.S.) and British Columbia (Canada).
A large reservoir of seawater exists in Earth's crust, which is thought to be the largest habitat on Earth. This seawater aquifer supports a dynamic microbial ecosystem that is known to eat hydrocarbons and natural gas,…
With Osama Bin Laden dead, conspiracy theorists will find a way to say it isn't him at all. Sure, a 6'4" thin guy can be replaced by decoys rather easily but science has come a long way since the September 11th, 2001 attacks that took Bin Laden from being a famous terrorist to being infamous - though given recent developments in the middle East and Africa, Bin Laden has ironically done more to promote democracy in the region than anyone, since the establishment of two democracies in retaliation for regional support for Bin Laden has had a domino effect.
Visual identification by a SEAL…
BRUSSELS, April 20, 2011 /PRNewswire/ -- Every person's intestinal system falls into one of three clearly distinguishable types of gut microbiota, comparable to blood types. These types are not related to race, native country or diet, according to a new metagenomics study by an international consortium of scientists including Jeroen Raes, of the VIB and Vrije Universiteit Brussel, published in Nature. Metagenomics is the study of the genetic material of complete ecosystems, in this case the human gut.
"The three gut types can explain why the uptake of medicines and nutrients varies from…
Is biology too important to be left in the hands of experts? Maybe.
Americans like stories about underdogs who start as outsiders but then become the very core of what being 'inside' means. Think Einstein and the patent office. Or Mendel, an 'uncertified substitute teacher' whose day job was being an Augustian monk but whose knowledge of amateur horticulture allowed him to win a race career biologists did not even know had started.
Outsiders doing important things appeals to the frontier spirit in Americans and there's nothing more like a wide open frontier than…
It's no secret that humans are not the only species with circadian rhythm - a biological clock. Studying red bread mold may teach us how our own internal clock works and by experimenting with the fungus’ response to light and darkness, researchers can explore its reaction to different substances, food and temperatures.
Basically, giving mold jet lag may help us mitigate it in humans.
Once every 24 hours, their red bread mold produces a new generation of spores called conidia. The mold is governed by a 24 hour circadian rhythm, controlled by its genes. This circadian rhythm will proceed…
Most are unaware of it but the evolutionary arms race between plants and plant diseases is always happening around us. Fungi are a major cause of plant diseases and are responsible for large-scale harvest failure in crops like maize and other cereals all over the world.
Researchers analyzed the genetic make-up of Sporisorium reilianum, an important maize parasite. Based on a comparison with the genome of a related fungal species, they succeeded in identifying new genes in maize infestation. The smut fungi Ustilago maydis and Sporisorium reilianum are parasites that attack…
Cephalove recently had a couple of lovely posts about that most famous of squid symbioses: the bobtail squid Euprymna scolopes and the bioluminescent bacteria Vibrio fischeri. It's become a model system for all kinds of questions about bacteria-host relationships, including pathogenic ones (read: bacterial disease). And it's an excuse to add adorable photos to otherwise not-very-photogenic stories about microbes! See:
The latest news to come out of all this research into V. fischeri is a new medical approach to fighting bacterial diseases. (And it's about time we got a new approach, because…
Chikungunya virus has been terrorizing some parts of the world by causing disease in humans through Aedes albopictus mosquitoes.
They belong to a family called alpha virus. Virulence can be attributed to the glycoproteins, E1 and E2 which also line the shell of the virus. Glycoprotein E1 is responsible for membrane fusion and E2 ( a product of cleavage of p62 by Furin, E3 being the second product) is responsible for receptor recognition. p62 and E1 exist as a precursor before Furin cleaves p62 into E2 and E3.
In a recent Letter to Nature, James E. Voss et al solved the structure of…
The RMS Titanic, which hit an iceberg and sank in 1912 and then was found by searchers in 1977, still has a few mysteries left.
A brand-new bacterial species dubbed Halomonas titanicae by scientists from Dalhousie University in Halifax and the University of Sevilla, was found aboard the Titanic and is contributing to its deterioration. The researchers isolated the Halomonas titanicae micro-organisms from a 'rusticle' collected from the Titanic, 3.8 km below the ocean surface.
Halomonas titanicae is able to adhere to steel surfaces, creating knob-like mounds of corrosion…