Cancer Research

REHOVOT, Israel and JERSEY CITY, New Jersey, August 19 /PRNewswire/ -- - Key Milestone Achieved With First Diagnostic Test Based on Company's microRNA Technology, Developed by Columbia University Medical Center, Approved for Clinical use - Acquires CLIA-certified lab to Expedite Commercialization of its microRNA-based Tests - Expands Pipeline With Three Additional microRNA-based Cancer Tests in Development Rosetta Genomics, Ltd. (NASDAQ: ROSG), a leading developer of microRNA-based diagnostic and therapeutic products, reported today its consolidated financial results for the quarter ended…

KVISTGARD, Denmark, August 19 /PRNewswire/ -- Today Bavarian Nordic published the company's interim report as of 30 June 2008. The full financial statements are available on the company's website. Below is an extract of the most significant matters in the report as well as events after the balance sheet date. In the first half of 2008 Bavarian Nordic generated revenue of DKK 23 million and recorded a loss before tax of DKK 119 million. The expectations for the financial result for the full year 2008 are maintained at revenues in the level of DKK 180 million, and a pre-tax loss in the level…

Scientists and consumers have known for years that grapefruit juice can increase the absorption of certain drugs — with the potential for turning normal doses into toxic overdoses. Now, the researcher who first identified this interaction is reporting new evidence that grapefruit and other common fruit juices, including orange and apple, can do the opposite effect by substantially decreasing the absorption of other drugs, potentially wiping out their beneficial effects. The study provides a new reason to avoid drinking grapefruit juice and these other juices when taking certain drugs,…

Sometimes you can improve on nature. Researchers have used a spice-based compound to develop synthetic molecules that are able to kill cancer cells and stop the cells from spreading - in the lab, anyway. The miracle spice? Turmeric; specifically curcumin, a naturally occurring compound it contains. Centuries of anecdotal evidence and recent scientific research suggest curcumin has multiple disease-fighting features, including anti-tumor properties. However, when eaten, curcumin is not absorbed well by the body. Instead, most ingested curcumin in food or supplement form remains in the…

A possible future way to prevent relapses into drug dependence has been discovered by researchers at Linköping University and the German cancer research center DKFZ. The target is the dopamine-producing nerve cells in the midbrain. Earlier research has shown that these cells become more excitable when a person takes drugs. To find out the functional meaning of this, these researchers used a mouse model for cocaine dependence. When they blocked the cells’ receptors for glutamate - the brain’s most important signal substance -the risk of relapsing into addiction vanished. The findings are being…

When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. In research in the August 15th issue of Genes & Development, Rockefeller University scientists using mice have figured out a way to amplify the signals that tell these precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction. The work, led by Hermann Steller, Strang Professor and head of the Laboratory of Apoptosis and Cancer Biology, is the first to reveal the mechanism by which a class of…

A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. The research, published recently in Genome Biology, describes how cancers can be divided into three groups distinguished by disparate developmental signatures. Isaac S Kohane from Children's Hospital Boston and Harvard University, US, led a team of researchers who performed a comprehensive comparison of genes expressed in early developmental stages of various human tissues and those expressed in different cancers affecting these tissues…

DENVER, August 13 /PRNewswire/ -- - One in Four Dogs Dies of Cancer - The Number One Cause of Death in Dogs Over the Age of Two Dogster.com, the world's most popular and comprehensive Web site devoted to the health and happiness of dogs, has joined Morris Animal Foundation (MAF) in its global effort to find a cure for canine cancer. Dogster will donate US$2 for every new subscription or subscription extension, through September 30. To subscribe go to http://www.dogster.com, scroll down on the home page to "site updates" and the help cure canine cancer link. By subscribing, dog lovers will…

KVISTGARD, Denmark, August 13 /PRNewswire/ -- Bavarian Nordic's US subsidiary, BN ImmunoTherapeutics has entered into a scientific partnership with the National Cancer Institute (NCI) in the United States. Under the Cooperative Research and Development Agreement (CRADA) the NCI and Bavarian Nordic will jointly develop new immunotherapies for the treatment of prostate cancer. Under the CRADA, BN ImmunoTherapeutics has rights to exclusively license intellectual property that results from this collaboration. Bavarian Nordic will in the future explore opportunities for extending this…

Researchers at Duke University Medical Center and at the National Institute of Environmental Health Sciences (NIEHS) say they have shown how broken sections of chromosomes can recombine to change genomes ... and spawn new species. The scientists used X-rays to break yeast chromosomes, and then studied how the damage was repaired. Most of the chromosome aberrations they identified resulted from interactions between repeated DNA sequences located on different chromosomes rather than from a simple re-joining of the broken ends on the same chromosome. Chromosome aberrations are a change in the…