Cancer Research

MUNICH, Germany, August 31 /PRNewswire/ -- - Sub-group analysis of landmark trial showed prasugrel substantially reduced risk of heart attack and stent thrombosis compared with clopidogrel among ACS patients with diabetes Patients who were diabetic and diagnosed with acute coronary syndromes (ACS) were 40 percent less likely to suffer a heart attack if they were treated with prasugrel vs. clopidogrel, according to a sub-group analysis of the TRITON-TIMI 38 trial (8.2 percent vs. 13.2 percent, P0.001). In addition, according to this same analysis, the combined rate of cardiovascular death,…

Scientific happenings, big and small, on this day in history But first, today’s quiz: The answer may seem obvious, but don’t be fooled – it’s not what you think. On this day in 1886, the first earthquake on record with significant human consequence (over 100 deaths) took place. In what U.S. state did it occur? Just to confirm, it’s NOT California. You can discover the answer at the end of this article. Now on to other events: EVENTS 1895 Design of the Zeppelin patented In 1895, Count Ferdinand von Zeppelin patented in Germany his invention of the rigid airship, known as the Zeppelin.…

UXBRIDGE, England, August 29 /PRNewswire/ -- NICE (National Institute for Health and Clinical Excellence) has published guidance that recommends Baraclude(R) (entecavir) as an option for treatment of eligible patients with chronic hepatitis B (CHB). Entecavir is a potent anti-viral treatment for chronic Hepatitis B that has been shown to be more effective at suppressing the virus than the most widely used anti-viral treatment (lamivudine)(1) and has shown minimal emergence of resistance in new patients treated with it (entecavir) for up to 5 years.(2) Richard Marsh, Director of External…

Johns Hopkins researchers say they have discovered the earliest form of human blood stem cells and deciphered the mechanism by which these embryonic stem cells replicate and grow. They also found a surprising biological marker that pinpoints these stem cells, which serve as the progenitors for red blood cells and lymphocytes. The research reported today used federally approved embryonic stem cell lines. The biochemical marker, angiotensin-converting enzyme (ACE), is well known for its role in the regulation of blood pressure, blood vessel growth, and inflammation. ACE inhibitors are already…

Radiation from the atomic bomb blasts in Hiroshima and Nagasaki, Japan, in 1945 likely rearranged chromosomes in some survivors who later developed papillary thyroid cancer as adults, according to Japanese researchers. Writing in Cancer Research, the scientists report that subjects who lived close to the blast sites, were comparably young at the time, and developed the cancer quickly once they reached adulthood, were likely to have a chromosomal rearrangement known as RET/PTC that is not very frequent in adults who develop the disease. "Recent in vitro and in vivo studies suggest that a…

STAINES, England, August 28 /PRNewswire/ -- - Not for distribution in the United Kingdom - Research Adds to Already Demonstrated Efficacy in Adult Population Parents and paediatricians are today welcoming the results of new research that adds additional support for an effective and well tolerated treatment for children with invasive candidiasis. The research, published today in the September edition of The Pediatric Infectious Disease Journal(i), demonstrates that Mycamine(R) (micafungin) delivers high success rates(*) (i) in the treatment of premature infants, babies up to four weeks old…

OSLO, August 28 /PRNewswire/ -- - Results Further Support the Clinical Profile of This Novel Anti-Cancer Agent Under Development to Improve the Survival of Patients With Hormone Refractory Prostate Cancer (HRPC) Algeta ASA (OSE: ALGETA), the Norwegian cancer therapeutics company, today announced that the primary objective of its BC1-03 Phase II pain palliation study was met. The study showed that even single doses of Alpharadin in patients with painful bone metastases could produce increasing clinical benefit with increasing dose. Pain palliation is an important quality of life benefit in…

Most people probably think of change when they hear the word evolution, but some of evolution's most amazing molecular inventions have stuck around hundreds of millions, even billions of years. The complex protein machinery needed to express genes, metabolize energy sources, reproduce sexually, and lay out body plans has remained in place largely unchanged in spite of the tremendous variety we see in the living world. These constant core cellular processes are why biologists could crack the universal genetic code by experimenting with bacteria, and why we gain insight into cell division and…

COPENHAGEN, August 27 /PRNewswire/ -- - Summary: Genmab Reports Results for the Six Month Period Ended June 30, 2008 Genmab A/S (OMX: GEN) announced today results for the six month period ended June 30, 2008. During this period, Genmab reported the following results: Genmab's revenues were DKK 277 million (USD 59 million) for the first half of 2008. In the same period of 2007, Genmab recognized revenues of DKK 280 million (USD 59 million). An operating loss of DKK 471 million (USD 100 million). This compares to an operating loss of DKK 119 million (USD 25 million) reported for the…

MELBOURNE, Australia, August 27 /PRNewswire/ -- Professor David Hill, Director of The Cancer Council Victoria, will commence in his role as President of the International Union Against Cancer (UICC) on 27 August 2008 at the World Cancer Congress in Geneva. The UICC is a powerful advocacy group with more than 300 member agencies including Cancer Research United Kingdom and the American Cancer Society. Under Professor Hill's leadership the UICC will drive the worldwide agenda improving cancer prevention and survival through its membership base. Professor Hill said Governments around the world…