Cancer Research

DALLAS, May 8 /PRNewswire/ -- Award-winning actress and Susan G. Komen for the Cure(R) Ambassador Cynthia Nixon is raising money for breast cancer by auctioning off two tickets to the world premiere of Sex and the City: The Movie. Nixon, who returns as Miranda Hobbes in the upcoming TV series spin-off film, is offering a pair of tickets to the May 12 world premiere in London in an online sale on auction website eBay (http://cgi.ebay.com/ws/eBayISAPI.dll?ViewItem&item=330234708943). (Logo: http://www.newscom.com/cgi-bin/prnh/20070122/NYM084LOGO ) The winner and a guest will be flown to…

Researchers at the OU Cancer Institute have identified a new gene that causes cancer, according to an article in Oncogene. The gene and its protein, both called RBM3, are vital for cell division in normal cells. In cancers, low oxygen levels in the tumors cause the amount of this protein to go up dramatically. This causes cancer cells to divide uncontrollably, leading to increased tumor formation. Researchers used new powerful technology to genetically “silence” the protein and reduce the level of RBM3 in cancerous cells. The approach stopped cancer from growing and led to cell death. The new…

A new approach to estimating tumor growth based on breast screening results from almost 400,000 women is published today in Breast Cancer Research. This new model can also estimate the proportion of breast cancers which are detected at screening (screen test sensitivity). It provides a new approach to simultaneously estimating the growth rate of breast cancer and the ability of mammography screening to detect tumors. The results of the study show that tumor growth rates vary considerably among patients, with generally slower growth rates with increasing age at diagnosis. Understanding how…

ABBOTT PARK, Illinois, May 7 /PRNewswire/ -- - Phase II Data Demonstrate Abbott's Most Advanced NNR Candidate ABT-089 Shows Strong Safety, Tolerability And Efficacy in Adults With ADHD Abbott (NYSE: ABT) and other leading scientists will present new Phase II data showing that ABT-089, a selective neuronal nicotinic receptor (NNR) agonist, is a potentially effective and safe treatment for adults with Attention-Deficit Hyperactivity Disorder (ADHD). The studies are being presented today at the American Psychiatric Association (http://www.psych.org/) 161st Annual Meeting in Washington, D.C.…

Rensselaer Polytechnic Institute graduating senior Jeffery Martin has put his basic knowledge of sugars to exceptional use by creating a lab-on-a-chip device that builds complex, highly specialized sugar molecules, mimicking one of the most important cellular structures in the human body - the Golgi Apparatus. Among the most important and complex molecules in the human body, sugars control not just metabolism but also how cells communicate with one another. Cells build sugars in a cellular organelle known as the Golgi Apparatus. Under a microscope, the Golgi looks similar to a stack of…

STAINES, England, May 7 /PRNewswire/ -- The European Medicines Agency (EMEA) has announced the marketing authorisation of Mycamine(R), Astellas Pharma Europe's treatment for invasive candidiasis, oesophageal candidiasis and prophylaxis of Candida infection in patients undergoing allogeneic haematopoietic stem cell transplantation. Mycamine(R) will initially be available in the U.K and across the European market shortly after this. Professor David Denning of The University of Manchester said of the announcement: "The approval of micafungin is very good news for patients with life-threatening…

A common weedkiller in the U.S., atrazine, already suspected of causing sexual abnormalities in frogs and fish, has now been found to alter hormonal signaling in human cells, scientists from the University of California San Francisco (UCSF) report. Atrazine is the second most widely used weedkiller in the U.S., applied to corn and sorghum fields throughout the Midwest and also spread on suburban lawns and gardens. It was banned in Europe after studies linked the chemical to endocrine disruptions in fish and amphibians. In studies with human placental cells in culture, the UCSF scientists…

Genetic variation in the DNA of mitochondria – the 'power plants' of cells – contributes to a person’s risk of developing age-related macular degeneration (AMD), say investigators in the first study to examine the mitochondrial genome for changes associated with AMD, the leading cause of blindness in Caucasians over age 50. “Most people don’t realize that we have two genomes,” said lead author Jeff Canter, M.D., M.P.H., an investigator in the Center for Human Genetics Research. “We have the nuclear genome – the “human genome” – that makes the cover of all the magazines, and then we also have…

A new study by UC Davis researchers provides evidence that methods using human bone marrow-derived stem cells to deliver gene therapy to cure diseases of the blood, bone marrow and certain types of cancer do not cause the development of tumors or leukemia. The study was published online in the May 6, 2008 issue of Molecular Therapy. "The results of our decade-long study of adult human stem cell transplantation shows that there is little risk of adverse events caused by gene transfer, and that adult human stem cells do not pose a cancer risk when implanted into different organs," said Jan…

NEWPORT NEWS, Virginia, May 6 /PRNewswire/ -- - Gamma Camera sales to be launched in Europe Dilon Technologies announced today that it has received CE Mark (Conformite Europeenne) approval for the commercial sale of the Dilon 6800 Gamma Camera in European Union member countries. The Dilon system is a high-resolution gamma camera that enables molecular imaging of the breast and other small organs for early cancer detection. "I am delighted that our high technology camera will now also be available to customers in Europe and other parts of the world that require the CE mark. The body of…