Cancer Research

CALGARY, Canada, May 14 /PRNewswire/ -- Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that that it has received a letter of approval from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) for its Clinical Trial Application (CTA) to begin a Phase II clinical trial using intravenous administration of REOLYSIN(R) in combination with paclitaxel and carboplatin in patients with advanced head and neck cancers. The principal investigator is Dr. Kevin Harrington of The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust. "Interim…

A study investigating aging in mice has found that hormonal changes that occur when mice eat significantly less may help explain an already established phenomenon: a low calorie diet can extend the lifespan of rodents, a benefit that even regular exercise does not achieve. “We know that being lean rather than obese is protective from many diseases, but key rodent studies tell us that being lean from eating less, as opposed to exercising more, has greater benefit for living longer. This study was designed to understand better why that is,” said Derek M. Huffman, the study’s lead author. The…

Common Sense 101: if benefits outweigh the costs, generally people will opt in to whatever action is under consideration. If you can prevent or reduce your chance of death from cancer by early screenings at a nominal fee, you will probably get screened. Now throw a twist into the equation. Say that screening is only 50 percent effective at catching early cancer. On the benefit side, screening will still prevent or reduce cancer. On the cost side, you may not catch a tumor; you may be exposing yourself to harmful radiation (which ironically could contribute to the cancer you’re trying to…

A team of Canadian researchers has completed a massive survey of the network of protein complexes that orchestrate the fundamental processes of life. In the online edition of the journal Science, researchers from the Université de Montréal describe protein complexes and networks of complexes never before observed – including two implicated in the normal mechanisms by which cells divide and proliferate and another that controls recycling of the molecular building blocks of life called autophagy. These processes are implicated in diseases such as cancers and autophagy has recently been shown…

ISTANBUL, Turkey, May 13 /PRNewswire/ -- - Japanese Pharmaceutical Company Establishes its own Turkish Subsidiary - Important Step in Global Expansion DAIICHI SANKYO, one of the world's leading research-driven pharmaceutical companies based in Japan, is establishing its own subsidiary in Turkey. The company, to be called DAIICHI SANKYO Ilaç Tikaret Ltd., will be headquartered in Istanbul and will initially focus on marketing the osteoporosis medication Evista (Raloxifen). "Entering the Turkish market represents a major step in the expansion of our global presence," said Reinhard Bauer, CEO…

SAN DIEGO, May 12 /PRNewswire/ -- - All Patients in Cohort 3 Demonstrated Improvement in T-Cell Responses Further Supporting the Therapeutic Potential of HspE7 Nventa Biopharmaceuticals Corporation (TSX: NVN) today announced positive immunological data from the third cohort of its ongoing Phase 1 clinical trial of its lead product candidate, HspE7, in patients with cervical intraepithelial neoplasia, or CIN, a precursor to cervical cancer. HPV 16 E7-specific T-cell responses were elicited in all four subjects in the study's third cohort following administration of 500 mcg of HspE7 and 1,000…

Everyone knows there is a lot of crazy stuff on the internet, but did you know there is a lot of great writing about genes, genetics, and human diseases? And believe it or not, sometimes these pieces are written by people who know what they're talking about. If you're looking for what's new in human genetics, you've come to the right place. Welcome to the 31st Gene Genie, a blog carnival dedicated to great blogging about human genes and how they impact our health. This Mother's Day edition includes an in-depth highlight of the growing industry of personalized genetics. Too Many Genes for…

Working at the University of Oxford and The Open University, Dr Lynne Cox and Dr Robert Saunders say they have found a fast and effective way to investigate important aspects of human aging. Their discovery of a gene in fruit flies means they can now be used to study the effects aging has on DNA. The researchers demonstrate the value of this model in helping us to understand the critical aspects of human aging at cellular, genetic and biochemical levels. Dr Lynne Cox from the University of Oxford said: "We study a premature human ageing disease called Werner syndrome to help us understand…

A protein that is indispensable for passing on an accurate copy of the genome from mother to daughter cells can be compared to a cowboy’s lasso, say scientists at the The FIRC Institute of Molecular Oncology Foundation (IFOM). It 'catches' chromosomes and ties them to a transitory structure assembled during cell division. Once they have been neatly tied up, the chromosomes await the end of replication to be equally distributed between the two daughter cells. But if the lasso doesn’t catch them, chromosomes end up being randomly scattered, with potentially disastrous genetic effects: should…

CLEVELAND, Illinois and ROTTERDAM, The Netherlands, May 9 /PRNewswire/ -- University Hospitals Case Medical Center and Cardialysis BV today announced that the Companies have the intention to found Cardialysis Cleveland to provide combined clinical drug development and medical imaging services to clients that are developing therapeutics or medical devices for cardiovascular indications in world wide studies. University Hospitals Case Medical Center is the primary hospital of Case Western Reserve University (CWRU) School of Medicine, a premier biomedical research institution in the United…