Cancer Research

STOCKHOLM, May 30 /PRNewswire/ -- - Report Benchmarks the Current State of Lung Cancer Care Across Europe The fragmented organization and management of lung cancer diagnosis and care in many European countries are exacerbating already poor survival rates amongst patients with the disease. That is the conclusion of a new report from a group of leading Swedish researchers published on http://www.comparatorreports.se (1). There is a great need to improve outcomes for patients with lung cancer. It is the most lethal form of cancer in Europe and causes between 15-28 per cent of all cancer deaths…

CHICAGO, May 30 /PRNewswire/ -- - Results presented at major U.S. cancer conference Agendia BV, a world leader in the rapidly evolving field of molecular diagnostics, announced today that data from two studies involving its MammaPrint(R) breast cancer prognosis test will be presented at the American Society of Clinical Oncology's (ASCO) annual meeting. Collectively, these findings show that MammaPrint, a prognostic test for breast cancer recurrence using a 70-gene signature, provides important information for more effective patient management. "These studies demonstrate the clinical utility…

SAN DIEGO, May 30 /PRNewswire/ -- Gen-Probe Incorporated (NASDAQ: GPRO) announced today that the Company has launched in Europe its APTIMA(R) HPV Assay, a highly specific molecular diagnostic test to detect high-risk strains of the human papillomavirus (HPV), which causes cervical cancer. The APTIMA HPV Assay has been CE marked and is currently available for sale in 13 European Union countries. "The CE marking and launch of our APTIMA HPV Assay in Europe reflect Gen-Probe's commitment to the development of novel, more accurate molecular diagnostic tests to detect life-threatening infectious…

Researchers at the University of Leeds say they have solved a medical condition that puzzled Hippocrates more than 2,000 years ago. The phenomenon of "finger clubbing", a deformity of the fingers and fingernails, has been known for thousands of years, and has long been recognized to be a sign of a wide range of serious diseases. Lung cancer, heart disease, hyperthyroidism, various gastrointestinal diseases and many other conditions all result in finger clubbing. But exactly why swollen, reddened fingers should be an indicator of serious illness has remained a mystery – until now. "It's one…

EDMONTON, Canada, May 29 /PRNewswire/ -- - TCH (Taxotere, Carboplatin, Herceptin) showed a significant improvement in Disease-Free Survival (DFS) and Overall Survival (OS), compared to AC-T (doxorubicin and cyclophosphamide followed by docetaxel) and a 5-fold lower cardiotoxicity compared to AC-TH (AC-T + Herceptin) in women receiving adjuvant therapy for HER2-positive ESBC The Cancer International Research Group (CIRG), a division of TRIO (Translational Research in Oncology) announced today that, based on its study BCIRG 006, the U.S. Food and Drug Administration (FDA) has approved a new…

TRONDHEIM, Norway, May 29 /PRNewswire/ -- - Randomised Double-Blind Trial Results Show Meaningful Pain Relief at 10 Minutes in Patients With Breakthrough Cancer Pain - Treatment Aimed at Opioid-Tolerant Patients With Cancer Experiencing Breakthrough Pain - New and Easy to Administer Analgesic Formulation Designed to Provide Fast Patient Benefit Meaningful pain relief at 10 minutes following dosing with intranasal fentanyl spray among patients with cancer who experience breakthrough pain was reported today at the Fifth Research Forum of the European Association for Palliative Care, in…

AMSTERDAM, May 29 /PRNewswire/ -- - Dr. Mielke Continues his Collaboration With Kiadis Pharma on ATIR(TM) Biopharmaceutical company Kiadis Pharma announces today the clinical development collaboration for its lead product ATIR(TM) with Dr. Stephan Mielke and Professor Dr. Hermann Einsele from the Allogeneic Stem Cell Transplant Center, Division of Hematology and Oncology, Department of Internal Medicine II at the Julius-Maximilians University of Würzburg, Germany. Principal investigator of this collaboration will be Dr. Mielke. Previously, Dr. Mielke initiated the ongoing phase II clinical…

By studying heat-loving microbes, two research teams have gained new insight into how seemingly small differences in a single protein involved in DNA transcription and repair can lead to strikingly different genetic disorders in humans. The two studies in the May 30th issue of Cell, a Cell Press publication, uncover the crystal structure and biochemical activity of an enzyme known as XPD helicase taken from Sulfolobus archaea, microbes distinct from bacteria that share many fundamental genes with humans. For reasons that had remained rather mysterious until now, point mutations in human XPD—…

LONDON, May 29 /PRNewswire/ -- - Odds of youth smoking uptake greatly reduced if parents quit If both parents of a child never smoked, research shows that a child's odds of daily smoking are reduced by more than 70 percent(1) compared to when both parents continue to smoke. And if both parents were smokers but quit, those same odds are reduced by nearly 40 percent.(1) Additional research shows that mothers who quit are less likely to have children who start smoking.(2) As global leaders in tobacco control commemorate World No Tobacco Day (WNTD) on May 31st, the rallying cry is to prevent…

Researchers at The University of Nottingham have taken some important first steps to creating a synthetic copycat of a living cell. Dr Cameron Alexander and PhD student George Pasparakis in the have used polymers — long-chain molecules — to construct capsule-like structures that have properties mimicking the surfaces of a real cell. In work published as a 'VIP paper' in the journal Angewandte Chemie International Edition, they show how in the laboratory they have been able to encourage the capsules to 'talk' to natural bacteria cells and transfer molecular information. The breakthrough could…