Increasing the amount of SUMO, a small protein in the brain, could be a way of treating diseases such as epilepsy and schizophrenia, reveal scientists at the University of Bristol, UK. Their findings are published online today in Nature.
Distribution of kainate receptors (blue) and SUMOylation enzymes (red) in the synaptic areas (green) of a hippocampal neurone. Credit: Stephane Martin
The brain contains about 100 million nerve cells, each having 10,000 connections to other nerves cells. These connections, called synapses, chemically transmit the information that controls all brain function…