Muscular Dystrophy: Alpha-Enolase And Plasmin Mechanism In Muscle Regeneration
Researchers have described a new selective target in muscle regeneration. This is the association of alpha-enolase protein and plasmin, findings which could be used to develop new treatments to regenerate muscular injuries or dystrophies.
Skeletal muscle has a great regeneration capacity after injury or genetic diseases, such as Duchenne muscular dystrophy, the most common neuromuscular disorder in children. This condition is due to a defect in the dystrophin gene, which absence causes instability of the membrane and leads to degeneration of muscle fibers. Regeneration involves the…