Omega-3s and Brain Function

Two papers in the latest issue of the American Journal of Clinical Nutrition provide more support for the idea that omega-3s improve brain function. The first was a cross-sectional study involving about 2000 persons 70-74 years old in Norway. Their fish consumption was measured and they took a battery of cognitive tests. The more fish you ate, the better your score on every test, even after adjustment for several things.

Two papers in the latest issue of the American Journal of Clinical Nutrition provide more support for the idea that omega-3s improve brain function.

The first was a cross-sectional study involving about 2000 persons 70-74 years old in Norway. Their fish consumption was measured and they took a battery of cognitive tests. The more fish you ate, the better your score on every test, even after adjustment for several things.

The second used data collected as part of a 3-year experiment about something else (the effect of folic acid) with 800 persons aged 50-70. They measured the omega-3 concentrations in the blood of their subjects. Would these predict anything? Their results were more ambiguous:

Higher plasma n–3 PUFA proportions predicted less decline in sensorimotor speed . . . and complex speed . . . over 3 y. Plasma n–3 PUFA proportions did not predict 3-y changes in memory, information-processing speed, or word fluency. The cross-sectional analyses showed no association between plasma n–3 PUFA proportions and performance in any of the 5 cognitive domains.

Cross-sectional correlations between a measure of omega-3 (fish consumption) and cognitive performance are exactly what the first study did find.

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