Clinical Trial of Oxytocin for Migraines

Trigemina, a company focused on creating non-narcotic pain
relief drugs, is enrolling patients in a Phase II clinical
trial of inhaled oxytocin
to treat chronic migraine. Trigemina's oxytocin
product, known as T1-001 (no doubt to be renamed to something lyrical if it
comes to market), has already shown promising results in preliminary studies,
the company says.

This
use makes perfect sense: Oxytocin is a general analgesic (pain reducer), and it
also contributes to relaxation and healing.

It's notable that
Trigemina specializes in inhalant drugs, and it has a proprietary
formulation of oxytocin. Without some market angle, there's little
incentive for companies to develop oxytocin-based drugs.

If and when this comes to market, I can see it being prescribed off-label for all kinds of things, including   persistent genital arousal disorder (PGAD) and fibromyalgia.

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