KLF15 Gene Produces Benefits Of Steroids Without The Side Effects
Scientists have revealed that glucocorticoids, a class of steroid hormones that are commonly prescribed as drugs, enhance muscle endurance and alleviate muscular dystrophy through activation of the gene KLF15. Critically, this pathway is not involved in muscle wasting or the other major detrimental effects of prolonged steroid use.
The discovery could lead to the development of new medications that improve muscle function without the negative consequences caused by long-term steroid exposure, especially important for progressive muscle wasting diseases like Duchenne's muscular dystrophy (DMD…