Cortisol For Post-Traumatic Stress Disorder?
Cortisol helps our bodies cope with stress, but what about its effects on the brain? A new study appearing in the October 15th issue of Biological Psychiatry, says that in an animal model of posttraumatic stress disorder (PTSD), high doses of a cortisol-related substance, corticosterone, prevented negative consequences of stress exposure, including increased startle response and behavioral freezing when exposed to reminders of the stress.
However, low-dose corticosterone potentiated these responses. This finding suggests that corticosterone levels may influence both vulnerability and…