Pharmacology
Regular, moderate coffee consumption may decrease an individual's risk of developing type 2 diabetes, according to research in a report published by the Institute for Scientific Information on Coffee.
More than 370 million people worldwide have diabetes making it one of the most significant health problems. To mark World Diabetes Day,
the Institute for Scientific Information on Coffee
released an updated report outlining the latest research on coffee and type 2 diabetes.
The updated report is based on a report from the World Congress on Prevention of Diabetes, held in…
Trastuzumab and anthracyclines given concurrently are effective at treating HER-2-positive breast cancer but there is worry that this could lead to increased risk of cardiac toxicity.
New research shows these agents do not need to be given concurrently to achieve a high rate of complete pathological remission. The findings investigated the timing of trastuzumab administration with anthracycline and taxane chemotherapy.
The randomized phase III trial enrolled 280 women with operable HER-2 positive invasive breast cancer at 36 centers across the United States from September 2007 through…
Researchers in a new paper say that one way to gauge the extent of prescription opioid pain reliever abuse is to count the number of health care providers.
In an analysis of opioid use and abuse, they found that access to health care increases the availability of prescription opioids, which, in turn, is associated with higher rates of opioid abuse and associated consequences. They conclude that the structure of local health care systems at the county level is a major determinant of community-level access to opioids.
As pain has become a more subjective, commonly-used symptom, the number of…
In recent years, approximately 4.4 million women in the U.S. have been diagnosed with bipolar disorder and women of childbearing age having the highest number of diagnoses.
A new study has found that physiological changes during pregnancy reduce the effects of lamotrigine, a drug commonly prescribed for people diagnosed with bipolar disorder, making women more vulnerable to recurring episodes. The new findings will help psychiatrists and physicians prevent bipolar manic and depressive symptoms during pregnancy, which are risky for the health of the mother and her unborn child.
There…
Glioblastoma multiforme (GBM) is a brain cancer that kills approximately 13,000 Americans a year. It is aggressive and incurable.
A research team has demonstrated delivery of a therapeutic delivered using nanotechnology that turns off a critical gene in this complex cancer, increasing survival rates significantly - in animals.
The drug is designed to target a specific cancer-causing gene in cells. The drug simply flips the switch of the troublesome oncogene to "off," silencing the gene, which knocks out the proteins that keep cancer cells immortal.
In a study of mice, the nontoxic drug…
Even brief usage of anabolic steroids may have long lasting, perhaps even permanent performance-enhancing effects, according to a new study.
It was previously believed that re-acquisition of muscle mass after periods of inactivity was due to motor learning. The new data from an investigation of the effects of steroids on muscle re-acquisition in mice suggests that there is a cellular 'memory mechanism' within muscle of brief steroid users.
The team investigated the effects of steroids on muscle re-acquisition in mice and discovered greater muscle mass and more myonuclei, which are…
A new analysis of data on over 3,000 elderly Americans strongly suggests that people over the age of 75 with normal cognition who used diuretics, angiotensin-1 receptor blockers (ARBs) and angiotensin-converting enzyme (ACE) inhibitors showed a reduced risk of AD dementia by at least 50 percent. In addition, diuretics were associated with 50 percent reduced risk in those in the group with mild cognitive impairment.
Beta blockers and calcium channel blockers did not show a link to reduced risk, the researchers reported.
Alzheimer's disease is a public health issue in aging population and the…
If you buy supplements, alternative medicines and advertised herbal gimmicks based on the claim that they are too progressive for the FDA, you are just lacking in judgment. If you are buying the workout supplement Craze, a product widely sold across the U.S. and online, you could be in a lot more danger.
A workout supplement marketed as a 'performance fuel', Craze is manufactured by Driven Sports, Inc. It is sold in stores across the United States and internationally via body supplement websites.
An international team of scientists have identified potentially dangerous amounts of…
'Natural' health products are all the rage among the segment of the population that doesn't trust science or medicine. But applying the ethical standards of the medical community to people operating outside the medical community can be a big mistake - the majority of herbal products on the market contain ingredients not listed on the label, with most companies substituting cheaper alternatives and using fillers, according to new research.
One product labeled as St. John's wort contained Senna alexandrina, a plant with laxative properties. It's not intended for prolonged use, as it can…
Observational studies have reported that statins improve outcomes of various infections. Ventilator-associated pneumonia (VAP) is the most common infection in the intensive care unit (ICU) and is diagnosed in approximately 8 to 28 percent of ICU patients receiving mechanical ventilation.
Ventilator-associated pneumonia is associated with increased mortality rates and high health care costs. New treatments are needed to improve the outcomes of VAP, according to background information in the article.
Laurent Papazian, M.D., Ph.D., of Hôpital Nord, Marseille, France, and colleagues…