Aging

Disclaimer: If you read this, don't blame me for whatever psychological damage that will inevitably follow.
This may not be the most dignified thing I've ever written, but I couldn't resist once I thought of the title. And, it also happens to be a real condition.
In fact, Cosmo, that bastion of science, has an article called "13 Problems Men Have With Their Balls," and this is one of the 13. If you've gotten this far, I'm guessing you're gonna read it, but don't expect to see something that is worthy of The New England Journal of Medicine.
But, old man balls (OMB) is one of the 13…

Nearly one in three British Columbia women over age 65 received inappropriate levels of prescription medicines in 2013, while only one in four men of the same age did, according to a new paper.
The work analyzed population-based health-care datasets to find out which medical and non-medical factors influence patients' risk of receiving prescription drugs on the American Geriatrics Society's list of drugs that should be avoided for older patients. The biggest non-medical risk factor was an individual's sex.
The authors found that, even when results were adjusted for all other risk factors,…

The hip fracture risk of farmers is lower than the general population , according to a study in Sweden, one of the few countries which tracks hip fractures through a national registry, making it possible to assess how hip fracture risk across the country according to occupation, economic status, level of education, latitude, and urban versus rural living.
Hip fracture risk is known to be correlated to physical activity, but that's one of the variables which the registries can't accurately track, since self-reported surveys about exercise are as useless in epidemiology as they are…

MINNEAPOLIS - Exercise in older people is associated with a slower rate of decline in thinking skills that occurs with aging. People who reported light to no exercise experienced a decline equal to 10 more years of aging as compared to people who reported moderate to intense exercise, according to a population-based observational study published in the March 23, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
"The number of people over the age of 65 in the United States is on the rise, meaning the public health burden of thinking and memory…

The best time to identify signs of obstructive sleep apnea may not be at night while snoozing in bed but, instead, while sitting in the dentist's chair.
Sleep apnea affects more than 18 million American adults, but many cases go undiagnosed, according to the National Sleep Foundation. Severe cases of the disorder are linked to cardiovascular disease, diabetes, depression, memory loss and more.
According to a new study, dentists are in a unique position to pinpoint signs of obstructive sleep apnea (OSA), a disorder in which breathing repeatedly stops and starts during sleep due to blocked…

The surgical approach to total hip replacement (THR)--either from the front of the body or the side/back (anterior versus posterior)--has no impact on outcomes six months after surgery, according to research presented today at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).
Total hip replacement is extremely common with more than 300,000 surgeries performed in the U.S. each year. Traditionally, most THRs have been done through a posterior approach, where the surgeon accesses the hip through the side or buttocks. More recently, anterior approach surgeries, where…

Passing on our genes to the next generation is the key process in evolution that happens through natural selection. So why do women suddenly stop having periods when they have at least a third of their lives left to live? It makes no sense, which is why it has been called a “Darwinian puzzle” – an aspect of biology that appears to be at odds with natural selection.
There are many competing hypotheses for why this may be the case, but so far there is no generally accepted theory. In our new study, published in Biology Letters, we evaluated and combined two of the main hypotheses to come up…

Researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration,
Inhibitors of the enzyme are being developed as a new anti-cancer target.
Aged and damaged cells frequently undergo a form of proliferation arrest called cellular senescence. These fading cells increase in human tissues with aging and are thought to contribute to age-related increases in both cancer and inflammation. The secretion…

Kidney stones are increasing in the U.S., a striking change from the historic pattern in which middle-aged white men were at highest risk for the painful condition.
Researchers, clinicians and public health experts have been aware of the overall increase in kidney stones in children and adolescents, but the current study provided greater clarity on the specific groups of patients at greatest risk by analyzing age, race and sex characteristics among children and adults in South Carolina over a 16-year period, from 1997 to 2012.
Drawing on state medical records, the study team analyzed data…

Life expectancy at birth is about six years shorter for White males than White females. This gap is about eight years for Blacks. Given the close correlation between declining health and early death, older males are effectively on average several years more aged than females. The detailed shapes of statistics could conceivably not support such ‘hyper-aging’, or it could conceivably result in only a few months of hyper-aging. The ‘Hyperaged Men Description’ is however strongly confirmed by the shape of for example Europe’s population pyramid. There is no far earlier onset of males dying, or…