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Phase 2 Study For Drug To Treat Marijuana Addiction

By Hank Campbell in Science 2.0
June 8, 2023
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Submitted by Hank on Thu, 06/08/2023 - 06:50
Old NID
256659

With increased legalization of marijuana across the United States came increased cases of addiction, and even greater negative outcomes because more of it is smoked.

In a phase 2a clinical study in volunteers with cannabis addiction, a compound named AEF0117, a type 1 cannabinoid receptor signaling-specific inhibitors (CB1-SSi) candidate, produced statistically significant reductions in the positive subjective and reinforcing effects of smoked cannabis.

AEF0117 is discovered and developed by Aelis Farma and based on a natural brain mechanism that combats CB1 receptor hyperactivity. 

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