The first double-blinded, placebo-controlled re-challenge trial investigating gluten-related symptoms found that ingesting 14 g/d of gluten did not induce gastrointestinal symptoms or fatigue in healthy people. There were no different effects than with a gluten-free placebo.
Which means if you gave up gluten and felt less fatigue, and you are not actually diagnosed with a gluten issue, it is likely other lifestyle changes that made you feel better.
This study was different than others in that it was not looking for effects of gluten in symptomatic populations and neglecting healthy controls, it was only for people who reported no effects from gluten. To see if gluten really was a problem or if it was just hype to sell products.
Unless you have a condition, it is just hype, according to the results.
After a decade as a diet fad, brought about by books like Grain Brain and Wheat Belly, the gluten-free thing may be over. Celiac patients certainly benefited, they became part of a booming $4 billion industry that provided a lot more choices than the limited fare of the past, but it also put them at substantial risk. If it was just a diet fad, like Lady Gaga et al., people might assume actual celiac patients were jumping on that bandwagon, and say something is gluten-free just to avoid drama. But gluten is literal poison for such people.
Among those for whom the diet fad is still a thing, this study won't change minds. People adopting it do so because they don't trust science or medicine, so they are not reading a study about gluten anyway.
